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September/October  2006

Screen Dreams: The Promise of Parallel Screening
In lead generation push, companies invest in tools that give more info earlier.
By Malorye A. Branca

Doubling Up on Targeted Therapies
Mixing and matching sparks new cancer hopes.

Actelion Is Reborn
Swiss firm acts to preserve its product pipeline.

Momenta Nabs Novartis Deal
Big Pharma betting on biogeneric future.

Briefings

Battle of the Super Statins
Next-generation pills rely on fixed combinations, new mechanisms.

Is Real FDA Reform at Hand?
By Nat Goodman

Pharmas Pickier About Trial Sites
Companies improve results by watching key metrics closely.

Building Better Monoclonals

Getting a Handle on Systems Biology

Diabetes Link Brings Hope
GSK-3 now hot neuro target for Alzheimer’s.

Building Bridges with Biomarkers
Traditional or genomic, they all involve pros and cons.

tech brief: Identifying and Qualifying Cross-Species Biomarkers

tech brief: Developing Biomarkers to Bridge Preclinical and Clinical

Big Pharma Launches into RNAi
Not wanting to miss the boat, pharma does RNAi deals.

Dealmakers: Major Pharma, Biotech, and Related Agreements  

Editor’s Note
On the threshold of systems biology.

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Cover IMAGE: MyoTube formation captured using GE’s IN Cell 1000 Analyzer.
Photo courtesy of GE Healthcare.