Features
Microarrays: Not Just for Genomics Anymore
By Todd Martinsky
This article discusses the impact and implementation of
ex situ miniaturization, parallelism and automation on
systems biology.
From Genome Sequence to Genome Understanding
By Steve Lombardi
This article describes the manufacturing methods and
probe set strategies required to develop microarrays
that can be used successfully in different life science
research experiments.
Redeveloping Microarray Data Treatment Methods for
Transcriptome Study
By Tomokazu Konishi
The author describes a data normalization method for
transcriptiome analysis based upon a parametric concept,
including the disclosed characteristics of the
transcriptome that form the bases of data comparisons.
A Bayesian Approach to Array Image Variability
By Nick Haan
This article briefly reviews current approaches to the
analysis of images generated by spotted DNA microarrays
and other array-based HTS platforms.
Beyond Expression Analysis: New Applications of
High-density DNA Microarrays
By Mark McCormick
Here, the author describes a variety of recent
microarray applications aimed at genome-wide comparative
genomics.
Substrate Architecture and Function
By Jens Sobek , Ralph Schlapbach
This article describes guidelines and considerations
involved in selecting functional surfaces for microarray
applications.