Cover Story
Implementation of HPLC
Automation for the Analysis and Purification of Chiral
Molecules
By Craig K. Esser , Regina M. Black , Derek Von
Langen
The authors describe the development and implementation
of an HPLC automation strategy in a big pharma research
department of more than 200 medicinal chemists for the
analysis and purification of chiral molecules.
Features
Improving Laboratory Animal
Studies Using Robotics
By Yongxin Zhu , Peter T. Kissinger , Candice B.
Kissinger
Here, the authors provide a progress report on an
evolving research program that uses a robotic system to
improve the quality and throughput for laboratory animal
studies while reducing the numbers of animals used and
enhancing animal comfort.
Technology
On-line and Off-line 2-D LC-ESI
MS-MS Methods in Proteomic Analysis
By Martin Vollmer , Edgar Nägele , Ralf Moritz
Off-line 2-D LC–MS-MS represents a powerful
alternative to on-line methodologies for protein
identification from complex proteomes. Here, the authors
provide a detailed comparison of the two techniques.
