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July/August 2006

Safety Biomarkers
Toxicology’s Holy Grail.
By Pete Mitchell and Malorye A. Branca

Related Coverage
Toxicogenomics Gaining Ground
By Nina Flanagan

Additional Online Content
FDA Tackles Drug Toxicity

By Pete Mitchell

Tailoring Breast Cancer Treatment
Prognostic testing turning into hotbed of
competition.

Waiting to Inhale
First airborne insulin hitting market.

Deals Bring Value to Biotech
Private-equity deals spark welcome trend in asset-rich industry.

OUTLOOK: Ernst & Young Says Biotech Looks Poised for Maturity

Drugmakers: Optimized for Failure?
By Nat Goodman
Pharma Urged to Register Early Trials
WHO proposal may or may not help industry, patients.
HDAC Inhibitors Surge Into Clinic
First market is small, but opportunities abound
RNAi Keeps Science on Its Toes
The honeymoon is over, but big rewards are closer.

TECH BRIEF: Expression Arrest Lentiviral shRNAmir: Mammalian RNAi Comes of Age

TECH BRIEF: Single-Cell Genetics by siRNA Ablation and Mutant Rescue: Pitfalls and Prospects

Thermo/Fisher’s Mega Footprint
Merger will likely reshape tool sectors of life, lab, and health sciences.

DEALMAKERS: Major Pharma, Biotech, and Related Agreements

Editors Note - Do More Trials and Better Science Equal Success?

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