Nanostream is a pioneer in the application of microfluidics to analytical
instrumentation. The company's first commercial product, the Nanostream
micro parallel liquid chromatography (μPLC) system, enables
high-throughput LC, providing 24 separations in parallel. Nanostream's
μPLC system is a fully integrated solution, including hardware, the
proprietary 24-channel Brio® cartridge, and software for both instrument
control and data analysis. The immediate benefits of the μPLC system
are increased speed and ease of use, with a 90% reduction in FTE needs,
and a 50-fold reduction in waste. The system enables applications
including separation-based assays for drug screening and sample
preparation for bioanalytical applications.
Chief Chromatographic Techniques
Supported
- Micro parallel liquid chromatography
- High performance liquid chromatography
- Reverse-phase HPLCUV absorbance detection
- Fluorescence detection
- Fraction collection
- Acquisition software
- Analysis software (Library Purity, Solubility, Permeability,
Ratiometric Assays)
Markets Served
The Nanostream μPLC system was developed after extensive market
research revealed a significant unmet need for greater analytical
throughput in drug discovery and development applications. With the demand
for increased throughput and productivity throughout the pharmaceutical
industry, Nanostream's customers span the drug discovery and development
space and include analytical chemists involved in compound library
management and formulation studies, biologists and biochemists involved in
assay development and HTS, as well as bioanalytical chemists in
pre-clinical DMPK groups.
Major Products/Services
The Nanostream micro parallel liquid chromatography (μPLC) system
(top, left) includes instrumentation, 24-column microfluidic Brio
cartridges and all necessary software for system control and data
analysis, thereby representing a fully integrated, stand-alone solution.
The system consists of an autosampler, pumps and Brio cartridges
compatible with a wide range of solvents as well as 24 UV absorbance (and
optional fluorescence) detectors that enable simultaneous, real-time
detection. Cartridges are available in a variety of columns and stationary
phases to optimize performance for specific experimental protocols.
Integrated plate-stacking system for either 96- or 384- well microtitre
plates and time-triggered fraction collection are also available.
Facilities
Nanostream has a 22,000 ft2 facility in Pasadena, California
where all of its R&D operations are conducted. In December 2003,
Nanostream opened its East Coast facility in Princeton, New Jersey.
Nanostream has an agreement with Japan's largest reseller, CTC Laboratory
Systems, to sell the μPLC system to the Japanese market.
Address:
580 Sierra Madre Villa Ave.
Pasadena, CA 91107
Telephone:
+1 (626) 351-8200
Fax:
+1 (626) 351-8201
E-mail:
sales@nanostream.com
Web Site:
www.nanostream.com/
Date Founded:
1999
Circle 17
